MTech Pharmaceutical Biotechnology syllabus for 2 Sem 2020 scheme 20BBC252

Module-1 INTRODUCTION 0 hours

INTRODUCTION:

Introduction to pharmaceutical biotechnology, pharmacokinetic concepts, current research trends, new advances and approved biologicals for pharmaceutical use and manufacturing principles. Quality assurance and control; Concept of GMP, GLP.

Module-2 THERAPEUTICS BASED ON BIOTECHNOLOGY 0 hours

THERAPEUTICS BASED ON BIOTECHNOLOGY:

Hematopoietic growth factor and coagulation factors,interferons and cytokines; Preparation andstandardization of hormones-thyroid, insulin and growthhormones; Enzymes-Enzymatic therapy and monographs;antibiotics and their derivatives-penicillin, streptomycin, tetracycline, cephalosporins, macrolides, peptide antibiotics (any two); vaccines BCG, DPT, Poliomyelitis, Typhus, toxoids-diptheria and tetanus; antitoxinsdiptheria and gasgangrene(any two); others-whole human blood, dried human plasma, gamma globulins, clinical dextran and absorbable haemostats, uses, and storage.

A d v e r t i s e m e n t
Module-3 BIOTRANSFORMATION 0 hours

BIOTRANSFORMATION:

Introduction, methods used in biotransformation, steroid transformation, contraceptives, L-Dopa, chemical reactions and mechanisms (hydroxylation, aromatization, synthetic routes, epoxidation and others), production and application of monoclonal antibodies.

Module-4 NUTRACEUTICALS 0 hours

NUTRACEUTICALS:

Antioxidants, flavanoids, carotenoids, cholesterol lowering chemicals, nutritional importance and their functions, deficiency diseases, nutritional status evaluation. Drug delivery systems: Introduction to drug delivery systems and methods, overview of barriers, calculation of drug metabolism and, pharmacodynamics.

Module-5 RECOMBINANT PROTEINS AND PROTEOMICS IN DRUG DEVELOPMENT 0 hours

RECOMBINANT PROTEINS AND PROTEOMICS IN DRUG DEVELOPMENT:

Role of proteomics in drug development Application of recombinant proteins in pharmaceutical industry, health care and future prospects.

 

Course outcomes:

At the end of the course the graduates should be able to

  • Demonstrate strong basics in principles of Pharmaceutical Biotechnology
  • Appreciate the ability to use biotechnology for sustainable development.
  • Understand the Molecular mechanisms of drug action

 

Question paper pattern:

The SEE question paper will be set for 100 marks and the marks scored will be proportionately reduced to 60.

  • The question paper will have ten full questions carrying equal marks.
  • Each full question is for 20 marks.
  • There will be two full questions (with a maximum of four sub questions) from each module.
  • Each full question will have sub question covering all the topics under a module.
  • The students will have to answer five full questions, selecting one full question from

 

Textbook/ Textbooks

1 Biopharmaceuticals: Biochemistry and Biotechnology Walsh G John Wiley & Sons Ltd 2003

2 Pharmaceutical :Fundamentals and ApplicationsBiotechnology Crommelin, Daan J. A., Sindelar, Robert D., Meibohm Springer 2013

 

Reference Books

1 Wolff Burger’s Medicinal Chemistry and Drug Discovery Manfred E Wiley & Sons, Inc 2000

2 Binghewang, Terunasiahaan, Richard soltero Drug delivery: principles and applications applications John wiley& sons 2005

3 Drug Metabolism: An Introduction Michael D. Coleman John Wiley & Sons, 2005

Categories

VTU Updates